Learn about the International Society of Amyloidosis

International Society of Amyloidosis (ISA), a non-profit organization of Scientists and Physicians engaged in research, teaching, or practice in connection with amyloid and amyloidosis. The aims of our Society are to promote research, education, clinical studies (including diagnosis and treatment), conferences and symposia on all aspects of amyloidosis worldwide.

  • Promote Research, Education & Clinical Studies
  • Attend Amyloidosis Conferences
  • Access Amyloid, The Journal

Learn more about the Society


ISA 2020 Content Now Online

Those who registered for ISA 2020 may access recorded presentations, discussions, abstracts and posters at the ISA 2020 site. If you have problems accessing this content, please email the secretariat. A PDF version of the program can be found here and a PDF version of the abstract book is available here.

World Amyloidosis Day, October 26, 2021

The objective for the first ever World Amyloidosis Day, organized by Amyloidosis Alliance and patient organizations from 18 different countries, spanning four continents, is to alert the world to the diagnostic delay that patients face. Find out more

ISA Workshop: Structure and Working Modalities of Amyloidosis Centers

June 24th, 2021 from 9 AM to 11 AM EDT (3 PM to 5 PM CEST)

During this virtual workshop, presenters from six established Amyloidosis Centers will discuss organizational structures and approaches, the potential to generate revenue from various modalities of consultation and key success factors. An additional presenter will discuss the challenges of forming an Amyloidosis Center in a low-resource environment.

Thank you to Global Bridges and Alnylam for sponsoring this workshop.

Registration Now Open-View Details!

ISA Workshop: Screening for ATTR Amyloidosis: Who, How, When?

July 22, 2021 from 9 AM to 10 AM EDT (3 PM to 4 PM CEST)

This virtual workshop will address controversies regarding screening for ATTR amyloidosis, particularly relevant to internists, neurologists, and cardiologists. Best practices for screening will be suggested. Following three recorded presentations, a live, 15-minute, moderated discussion will be held to answer viewers' submitted questions. 

Thank you to Global Bridges and Alnylam for sponsoring this workshop.

Registration Now Open-View Details!

J&J and Janssen Announce Challenge and Funding

Johnson & Johnson Innovation together with Janssen Global Services is now inviting innovators to submit ideas aimed at optimizing AL amyloidosis disease detection and early diagnosis in the Improving DEtection of AL Amyloidosis (IDEA) QuickFire Challenge. Multiple awardees with the best products, technologies, or methodologies will receive grant funding and other support. View details



Join the International Society of Amyloidosis and get a free AMYLOID, The Journal subscription.

The current Board of Directors of the ISA was officially elected for the next term via electronic vote on March 4, 2020.

Since 2002, the ISA has had exceptional leadership from around the world. We value their dedication and efforts that have led the organization in progressing the advancement of amyloidosis research.

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New online ISA application

We have made the ISA membership application and renewal process easier!

What Do You Think of the Updated Website?

In order to provide members of the ISA community the best experience possible, we’ve...

Amyloidosis: The Disease What is amyloid?

Amyloid fibrils are structures in which misfolded proteins are deposited in tissue and organs. Different proteins can be deposited as amyloid in various sites of the human body. When in a piece of tissue (a so-called biopsy) these deposits are viewed under a microscope in normal light, the material looks amorphous. However, if the same deposits are viewed under an electron microscope with higher magnification, massive amounts of small non-branching amyloid fibrils can be seen. When a biopsy is stained with Congo red dye, the deposits will stain red. A characteristic feature of amyloid is that these red deposits will turn into apple green if viewed in polarized light. When amyloid deposition leads to signs and symptoms of disease it is called amyloidosis.

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Tissue biopsy with amyloid fibrils stained red